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SC Hotel Guide

Access South Carolina offers online hotel reservations for most cities and the best rates available. Enjoy shopping for hotels and inns with the ability to book online 24 hours a day! Signature Reservations provides no-charge site selection services to corporate, association government clients or family reunions, athletic and school groups that plan off-site meetings, conferences and specialty groups in South Carolina. On their behalf, we research hotels and other meetings venues that match their criteria. Please complete our group booking request form so that we may assist you. group booking request. We are here to serve you. Please let us know how we can help you!



Arrival Date
Departure Date
Adults
Children
Holiday Inn Express Hotel & Suites Orangeburg, Sc
118 Sleep Inn Road
Orangeburg, SC 29118
Nightly Rates (115.00 - 149.00)   3 Star
Holiday Inn Express Hotel & Suites Orangeburg, Sc $hotle.Name
Welcome to Orangeburg, the Garden City of South Carolina and home of Edisto Memorial Gardens. Centrally located, Orangeburg is an area of great natural beauty, ideal climate & friendly people, famous for our Southern Charm and Heritage. A g...more
Howard Johnson Express Inn
3608 Old St. Matthews Rd.
Orangeburg, SC 29115
Nightly Rates (46.76 - 60.01)   1 Star
Howard Johnson Express Inn $hotle.Name
Newly Renovated In 2008 Conveniently located off I-26, Exit 145A, 35 miles southeast of Columbia and 75 miles northwest of Charleston, SC. Were are just 20 miles from I-95 south and 23 miles from I-95 north. We are close to South Caroli...more
Quality Inn & Suites
1415 John C. Calhoun Dr.
Orangeburg, SC 29115
Nightly Rates (69.99 - 74.99)   3 Star
Quality Inn & Suites $hotle.Name
Near South Carolina State University and Claflin University. Property features include: pool, fitness room, restaurant, lounge, meeting space for over 200, suites. Pet accommodation: 10.00/stay per pet. City - I-26 Exit 145A...more
SUPER 8 MOTEL - ORANGEBURG
610 John Calhoun Drive
Orangeburg, SC 29115
Nightly Rates (57.00 - 57.00)   1 Star
SUPER 8 MOTEL - ORANGEBURG $hotle.Name
* Welcome to the Super 8 Motel in Orangeburg * We are conveniently located in town, walking distance to the University * Small pets are welcome, just $10 per pet * 46 well appointed, exterior corridor rooms * Easy, drive up access * Free...more
Orangeburg - Days Inn South
Route 2 Box 215
Orangeburg, SC 29115
Nightly Rates (62.01 - 62.01)   2 Star
Orangeburg - Days Inn South $hotle.Name
Days Inn Conveniently Located Off I-26 Close between Columbia, SC and Charleston, SC. Easy access I-26 Exit 154B(US 301) Quiet and Relaxing, Restaurant on Property. Just the right place to stay after a long day of driving Directly off of th...more
Best Western Orangeburg Inn & Suites
746 Citadel Road
Orangeburg, SC 29118
Nightly Rates (89.99 - 89.99)   2 Star
Best Western Orangeburg Inn & Suites $hotle.Name
The Best Western Orangeburg Inn and Suites of Orangeburg, South Carolina is conveniently located off of exit 145a and 1-26. Our hotel offers amenities that fit the leisure or business traveler. Enjoy our heated indoor pool, free Internet ...more
Sleep Inn Orangeburg
3689 St. Matthews Rd
Orangeburg, SC 29115
Nightly Rates (84.99 - 84.99)   2 Star
Sleep Inn Orangeburg $hotle.Name
Stay at the Sleep Inn Orangeburg and start your day out right with our complimentary Mornign Medley Breakfast featuring hot, fresh Belgian waffles and a free USA Today (M-F). All of our interior corridor guest rooms are well appointed with ...more
Country Inn & Suites By Carlson, Orangeburg, SC
731 CITADEL ROAD
Orangeburg, SC 29118
Nightly Rates (69.00 - 99.00)   2 Star
Country Inn & Suites By Carlson, Orangeburg, SC $hotle.Name
Country Inn & Suites Orangeburg features 81 guest rooms and suites with free High Speed Internet access, microwaves, refrigerator and coffeemakers in every room. Meeting space for up to 100 attendees. Fitness room and business center with...more
Comfort Inn & Suites
3671 Saint Matthews Rd.
Orangeburg, SC 29115
Nightly Rates (89.99 - 114.99)   2 Star
Comfort Inn & Suites $hotle.Name
Easy on & off interstate access. The Comfort Inn & Suites is conveniently located less than one mile from the Orangeburg Regional Medical Center. This Orangeburg hotel is close to popular area attractions, including South Carolina State Uni...more
Fairfield Inn By Marriott Orangeburg
663 Citadel Road
Orangeburg, SC 29115
Nightly Rates (94.00 - 144.00)   2 Star
Fairfield Inn By Marriott Orangeburg $hotle.Name
Get FREE high-speed Internet access at this Fairfield Inn

Always fresh, always clean, our 65 guest rooms are full of thoughtful amenities, including a well-lit work desk and a remote-controlled TV with free cable. We'll get you st...more

Southern Lodge
3616 St Matthews Rd
Orangeburg, SC 29118
Nightly Rates (69.95 - 89.95)   2 Star
Southern Lodge $hotle.Name
Pause at Southern Lodge, an affordable Orangeburg SC hotel amid the quiet life of ease in affable America- Country air, fertile soil, abundant wildlife and the world famous Edisto Gardens165 acre rose park. Savor the simple pleasures, inclu...more
Jameson Inn Orangeburg
2350 Chestnut Street NE
Orangeburg, SC 29115
Nightly Rates (74.99 - 74.99)   1 Star
Jameson Inn Orangeburg $hotle.Name
Featuring true Southern Hospitality, Legendary Service, white colonial design, Deluxe Breakfast, clean comfortable rooms, fitness center & sparkling pool. Close to area attractions, you will enjoy the convenience of a contemporary hotel wit...more
Nearby Cities:
HarleyvilleOrangeburgSaint GeorgeSantee


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