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SC Hotel Guide

Access South Carolina offers online hotel reservations for most cities and the best rates available. Enjoy shopping for hotels and inns with the ability to book online 24 hours a day! Signature Reservations provides no-charge site selection services to corporate, association government clients or family reunions, athletic and school groups that plan off-site meetings, conferences and specialty groups in South Carolina. On their behalf, we research hotels and other meetings venues that match their criteria. Please complete our group booking request form so that we may assist you. group booking request. We are here to serve you. Please let us know how we can help you!



Arrival Date
Departure Date
Adults
Children
Sleep Inn Florence
1833 Florence Park Dr.
Florence, SC 29502
Nightly Rates (65.99 - 69.99)   2 Star
Sleep Inn Florence $hotle.Name
Inside corridor rooms. Restaurants within walking distance. In-room safe warranty fee: 1.00 per night. City - I-95 at ex. 164...more
Super 8 Motel - Florence
1832 1/2 W. Lucas St.
Florence, SC 29501
Nightly Rates (56.96 - 64.96)   1 Star
Super 8 Motel - Florence $hotle.Name
* Welcome to the Super 8 Florence, SC * Easy Access from I-95 * Property is Conveniently Located near Shopping, Restaurants, Entertainment and Local Attractions * Property has Clean, Comfortable Rooms and Friendly staff * Cra...more
Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327
2101 FLORENCE HARLEE BLVD
Florence, SC 29506
Nightly Rates (105.00 - 135.00)   2 Star
Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327 $hotle.Name
Welcome to the Holiday Inn Express Hotel & Suites Florence South Carolina.This premiere hotel is superbly located in the suburbs of Florence, SC, away from the hustle and bustle for a great night sleep but just minutes to Florence Regional ...more
Quality Inn & Suites Civic Center
150 Dunbarton Dr
Florence, SC 29501
Nightly Rates (79.99 - 124.99)   2 Star
Quality Inn & Suites Civic Center $hotle.Name
The Quality Inn is located 10 miles to Darlington Raceway, 8 miles to the airport and walking distance to Magional Mall, Civic Center, Outback Steak House, Olive Garden, and Chuck E Cheese. The Freedom Florence Complex is 10 miles. Business...more
Wingate by Wyndham - Florence
2123 West Lucas St.
Florence, SC 29501
Nightly Rates (85.01 - 99.01)   3 Star
Wingate by Wyndham - Florence $hotle.Name
Our convenient airport location (just 10 minutes away) and proximity to shopping, dining and entertainment makes us the hotel of choice among serious business travelers. At Wingate by Wyndham Florence we are prepared to meet the needs of b...more
Best Western Inn
1808 West Lucas Street
Florence, SC 29501
Nightly Rates (72.99 - 79.99)   2 Star
Best Western Inn $hotle.Name
Take time out to relax at the Best Western Inn, Florence, South Carolina. Where the employees make you feel at home. You can enjoy our complimentary deluxe continental breakfast in the lobby from 6:30 a.m. to 9:30 a.m. daily. We are the be...more
Ramada Inn Florence SC
3311 Meadors Road
Florence, SC 29502
Nightly Rates (55.01 - 75.01)   1 Star
Ramada Inn Florence SC $hotle.Name
The Ramada at Young's Plantation of Florence, SC is conveniently located at Exit 157 US 76. The hotel is a great halfway point on I-95 for travelers heading north or south. The Ramada at Young' s Plantation has 120 well appointed rooms feat...more
Holiday Inn Express Hotel & Suites FLORENCE CIVIC CENTER @ I-95 &
3440 WEST RADIO DRIVE
Florence, SC 29501
Nightly Rates (109.00 - 119.00)   2 Star
Holiday Inn Express Hotel & Suites FLORENCE CIVIC CENTER @ I-95 & $hotle.Name
Come experience the difference at the Holiday Inn Express Hotel & Suites in Florence, SC! Location! Located in the heart of Florence, we are surrounded by many great restaurants and shopping such as the Magnolia Mall, Commons Place Shoppin...more
Holiday Inn Hotel & Suites Florence-I-95,Sc
1819 West Lucas Street
Florence, SC 29501
Nightly Rates (76.00 - 85.00)   2 Star
Holiday Inn Hotel & Suites Florence-I-95,Sc $hotle.Name
Enjoy a taste of 'Southern Hospitality® at Holiday Inn Hotel&Suites in Florence,SC. We are conveniently located off I-95, exit 164. Only minutes from:Florence Airport, Amtrak, Powers Aviation, Civic Center, Freedom Florence, among other...more
Fairfield Inn By Marriott Florence
140 Dunbarton Drive
Florence, SC 29501
Nightly Rates (79.00 - 94.00)   2 Star
Fairfield Inn By Marriott Florence $hotle.Name
Enjoy our Southern Hospitality at our beautiful Fairfield Inn in Florence, SC. We offer friendly exceptional service with comfortable rooms, great amenities and complimentary high speed internet. We now feature Executive Rooms with microw...more
Comfort Inn Florence
1916 West Lucas Street
Florence, SC 29501
Nightly Rates (224.99 - 224.99)   2 Star
Comfort Inn Florence $hotle.Name
We are a pet friendly hotel and also offer an increased percentage of 20% off for AAA and AARP. All rooms have irons/ironing boards and hairdryers. In-room safe warranty fee: 1.50 per night. Pet Accommodation: 10.00 per night per pet. Subu...more
Ramada Inn
2038 W. Lucas Street
Florence, SC 29501
Nightly Rates (203.13 - 203.13)   2 Star
Ramada Inn $hotle.Name
The Ramada of Florence, SC is located at I-95 Exit 164 US 52 and is an excellent halfway point for those I-95 travelers heading north or south. The Ramada hotel offers guests both interior and exterior private entrances to clean, comfortabl...more
Florence Howard Johnson Express Inn - Florence, Sc
3821 Bancroft Rd.
Florence, SC 29501
Nightly Rates (63.96 - 63.96)   1 Star
Florence Howard Johnson Express Inn - Florence, Sc $hotle.Name
An Award Winning, AAA approved property, conveniently located off I-95, Exit 157, just 3 miles south of the 1-20 intersection. This is a perfect stopping point between Florida and New York, close to Darlington Raceway (10 miles), Florence...more
Florence - Days Inn South
I-95 & US 76 (Exit 157)
Florence, SC 29501
Nightly Rates (55.01 - 55.01)   3 Star
Florence - Days Inn South $hotle.Name
* Newly Renovated * Golf Packages Available * AARP/AAA 20% discount off rack rate * 4 Sunburst Rating * Shopping nearby * Magnolia Mall 3 mi * Florence Mall 4 mi. * Additional restaurants nearby * McLeod Regional Medical ...more
Florence - Days Inn I-95/North
2111 W Lucas St.
Florence, SC 29501
Nightly Rates (52.96 - 52.96)   3 Star
Florence - Days Inn  I-95/North $hotle.Name
Days Inn Florence North Exit 164 I-95 I -95 and Hwy 52 King W/Micro-Refrig Queen Rms 2 Beds W/Micro-Refrig Free Cable TV w/ HBO, ESPN, ESPN2, CNN,FOX,TNT, plus 58 more channels King Jacuzzi w Double Pull Out Sofa Free Daybreak Continental B...more
Residence Inn Florence
2660 Hospitality Boulevard
Florence, SC 29501
Nightly Rates (101.00 - 149.00)   3 Star
Residence Inn Florence $hotle.Name
Residence Inn by Marriott? is the extended-stay hotel that helps you feel connected while away from home and maintain a balance of work and life. Our homelike surroundings invite you to relax, and our community atmosphere will make you feel...more
Courtyard By Marriott Florence
2680 Hospitality Boulevard
Florence, SC 29501
Nightly Rates (109.00 - 109.00)   3 Star
Courtyard By Marriott Florence $hotle.Name
Located near the intersection of I-95 and I-20, the Courtyard of Florence is in the heart of Florence's retail, dining and entertainment district. You will be moments away from the finest shopping and dining in Florence. Concerts and Conv...more
Florence Travelodge
3783 W. Palmetto St.
Florence, SC 29502
Nightly Rates (45.01 - 45.01)   1 Star
Florence Travelodge  
An excellent stopping point between Florida and New York, our hotel is conveniently located on I-95 exit 157, just 6 miles South of the I-20 Intersection. Popular area attractions including Darlington Raceway (12 miles), Freedom Floren...more
Red Roof Inn Florence
2690 David McLeod Boulevard
Florence, SC 29501
Nightly Rates (54.99 - 64.99)   2 Star
Red Roof Inn Florence $hotle.Name
Easily accessible from I-95 and I-20, the Florence Red Roof Inn is within walking distance of many restaurants, a 13-screen movie theater and the Magnolia Mall with over 70 stores. This Inn is just 10 miles from the Darlington Internationa...more
Microtel Inn and Suites Florence
1912 Enterprise Drive
Florence, SC 29502
Nightly Rates (47.95 - 57.95)   1 Star
Microtel Inn and Suites Florence  
Microtel Inn and Suites Florence, SC - Enjoy a Quality Hotel Room at a Discount Hotel Price. Enjoy consistency, quality, reasonable prices and great service each time you stay with Microtel Inns and Suites. Microtel is one of the fastest-g...more
Microtel Inn and Suites Florence
1912 Enterprise Drive
Florence, SC 29502
Nightly Rates (47.95 - 57.95)   1 Star
Microtel Inn and Suites Florence  
Microtel Inn and Suites Florence, SC - Enjoy a Quality Hotel Room at a Discount Hotel Price. Enjoy consistency, quality, reasonable prices and great service each time you stay with Microtel Inns and Suites. Microtel is one of the fastest-g...more
Springhill Suites By Marriott Florence
2670 Hospitality Boulevard
Florence, SC 29501
Nightly Rates (109.00 - 109.00)   2 Star
Springhill Suites By Marriott Florence $hotle.Name
For GPS & mapping systems use - 2670 Hospitality Blvd, Florence SC 29501. Celebrate life and great travel at SpringHill Suites, Florence SC. Marriott's studio suite hotel is designed with up to 25% more room for working, relaxing and sle...more
Country Inn & Suites By Carlson Florence
1739 MANDEVILLE ROAD
Florence, SC 29501
Nightly Rates (71.00 - 114.99)   3 Star
Country Inn & Suites By Carlson Florence $hotle.Name
Hotel features complimentary continental breakfast, complimentary local calls. Spacious guest rooms feature desk, coffeemaker, iron/board, hairdryer, cable TV with HBO, AM/FM alarm clock radio, wireless internet. All suites additionally fea...more
Baymont Inn and Suites Florence
1826 West Lucas Street
Florence, SC 29501
Nightly Rates (53.10 - 59.00)   3 Star
Baymont Inn and Suites Florence  
Baymont Inn and Suites is conveniently located right off I-95. Surrounded by many great places to Shop and Dine. Hotel has High Speed internet and an Outdoor Pool. All Guest Rooms offer Clock, Coffeemaker, Iron and Ironing Board and Hairdy...more
Guesthouse Intl Florence
2001 W LUCAS ST
Florence, SC 29503
Nightly Rates (115.82 - 181.80)   2 Star
Guesthouse Intl Florence $hotle.Name
The GuestHouse International Inn is a beautiful property located on 7 acres of spacious, landscaped grounds. There are 16+ restaurants located right at our exit including Cracker Barrel & Ruby Tuesday. We are only 5 minutes away from the Ci...more
Country Hearth Inn Florence
831 South Irby Street
Florence, SC 29501
Nightly Rates (49.00 - 59.00)   3 Star
Country Hearth Inn Florence  
Cozy Lobby With Fireplace And Small Reading Library. 102 Rooms With King Or Double Beds. Four -4- Jr. Suites With Couch, Refrigerators Microwave, Hairdryers. Located Just South Of Downtown Florence. Near Timrod Park, Freedom Florence, Movie...more
Nearby Cities:
DillonFlorenceHartsvilleLake CityLattaMarionTimmonsville


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